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KMID : 0359320010410040455
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Korean Journal of Veterinary Research
2001 Volume.41 No. 4 p.455 ~ p.465
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Morphological study of GFAP-immunoreactive cells of fetal and neonatal spinal cords of Korean native goat
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송치원/Song, Chi-Won
정수연/이근좌/이강이/이경열/박일권/박미선/Chung, Soo-Youn/Lee, Keun-Jwa/Lee, Kang-Iee/Lee, Kyoung-Youl/Park, Il-Kwon/Park, Mi-Sun
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Abstract
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Glial fibrillary acidic protein(GFAP) is one of the intermediate filaments, and used as an astrocyte detection marker. GFAP distribution has been studied on the fetal, neonatal and aged brains.
In this study, the GFAP immunoreactive cell localization and distribution in the fetal (30, 45, 60, 90, 105 and 120 days of gestation) and neonate spinal cords of Korean native goat were investigated by immunohistochemistry. Nonpolar radial glial cells initiated to appear at 45 days of gestation. GFAP-immunoreactive processes were extended from central canal to pia matter. Bipolar immumoreactive cells were transformed to monopolar and multipolar immunoreactive cells at 45 days of gestation. Multipolar astrocytes of 60 days of gestation were found within white and gray matters of spinal cord. The number of GFAP-immunoreactive cells were gradually decreased from 90 days of gestation until newborn neonate. The intensity of GFAP immunoreactivity was gradually decreased from 95 days of gestation until newborn neonate. These results suggest that the radial glial cells within the gray and white matters of spinal cord are very fast developed.
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